Ibrance 100 mg tablet

Ibrance 100 mg tablet (palbociclib) may be used to treat adults with HR-positive, HER2-negative breast cancer that has spread to other parts of the body. Ibrance is used in combination with an aromatase inhibitor as the first hormonal-based therapy, or fulvestrant in those with breast cancer progression following hormonal therapy. Ibrance’s mechanism of action involves blocking proteins involved in cell division called cyclin-dependent kinases (CDK), specifically CDK 4 and 6. By blocking these proteins,Ibrance 100 mg tablete prevents cancer cells from dividing and multiplying uncontrollably. HR+ breast cancer cells rely heavily on CDK 4/6 for growth. Ibrance is a cancer medicine that interferes with the growth and spread of cancer cells in the body. Ibrance is not chemotherapy it is a targeted treatment

Ibrance 100 mg tablet Drug interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.Other medications can affect the removal of palbociclib from your body, which may affect how palbociclib works. Examples include azole antifungals (such as itraconazole, ketoconazole), carbamazepine, phenytoin, rifamycins